Statistics versus animal welfare: Validation of the experimental unit in the focus of 3R
Miriam Vogt, Samantha K. Balcerzak, Till Merlin Lohr, Sabine Chourbaji · FENS Forum 2024
To justify animal experiments, all methods require State-of-the-Art techniques. Statistics belong to often ‘unloved’ methods but reduce subjects by biometrical predictions, statistical analyses, and, surprisingly, by correct identification, i.e. the experimental unit (EU). Per definition, the EU is the number of subjects that can be treated individually different within the experiment. Consequently, correct implementations of EUs increase animal numbers when ‘treatment’ applies grouped housed animals, because the cage, independent of number of animals, is the EU. Thus, either ignore sociabilit
ePoster · Neuroscience