Topic: anomalous subjective experience

Tremendous progress has been made in treating psychotic disorders, although available pharmacotherapy remains insufficient. Symptoms related to reality misinterpretation are key for diagnosis but challenging in preclinical research. In humans, the Mirror-Gazing test has been employed to examine abnormal self-experience and to predict a risk of schizophrenia manifestation. The lack of corresponding animal methods impedes the development of novel drugs for early antipsychotic interventions. We established a task to evaluate anomalous subjective experience in rats using a mirror test. Initially,