Large-scale cortical reorganization in the premotor-parietal connections of a macaque model with primary motor cortical lesion and recovery
Tatsuya Yamamoto, Yuko Yoshida, Takayuki Ose, Yumi Murata, Takuya Hayashi, Noriyuki Higo · FENS Forum 2024
Neuromotor systems can functionally recover after local damage, but changes in the underlying cortical network remain unclear. In a nonhuman primate model of primary motor cortex (M1) lesions and motor recovery, we previously reported reorganization of subcortical output projections from the ipsilesional ventral premotor cortex (ip-PMv) to the cerebellum. In this study, we investigated the rewiring of cortico-cortical connections between the ip-PMv and parietal cortex using the same model. We injected biotinylated dextran amine (BDA) into the ip-PMv and compared the BDA labeling in the areas a
ePoster · Neuroscience