Ferulic acid supplementation ameliorates lindane neurotoxicity: The effects on anxiety-like behavior
Dragan Hrnčić, Nikola Šutulović, Vladimir Bošković, Mladen Mirković, Milena Vesković, Dušan Mladenović, Yavuz Dodurga, Mucahit Seçme, Nebojša Radunović, Djuro Macut, Aleksandra Rašić-Marković, Olivera Stanojlović · FENS Forum 2024
Lindane is organochloride environmentally persistent pollutant used manly as pesticide. Neurotoxicity of lindane is manifested through cellular and behavioral changes including expression of anxiety, seizures and lethal outcome in higher doses. Ferulic acid is polyphenol organic compound with antioxidant and anti-inflammatory effects in different tissues including neuroprotective effects in acute and chronic application. We hypothesized that it could ameliorate some of the lindane neurotoxic effects. Therefore, we investigated the effects of ferulic acid chronic supplementation on anxiety-like
ePoster · Neuroscience