Topic: arena exploration

Social withdrawal in the sub-chronic phencyclidine (PCP) rat model, a behavioral correlate of the negative symptoms of schizophrenia, is probably the most well-studied; yet, little is known about the altered psychological processes underlying this behavioral deficit. Despite the complex nature of social behavior, social interaction is indeed often simplified to a single readout parameter (e.g., total time spent in social interaction) that has limited explanatory power. Therefore, we developed a comprehensive ethogram of the social, as well as non-social (i.e., self-oriented behaviors and arena