Effect of enriched environment and aripiprazole on selected behavioral outcomes and neurogenic markers in animal model of PTSD
Jana Osacka, Lila Dziewiczova, Lubica Horvathova, Andrej Tillinger · FENS Forum 2024
Post-traumatic stress disorder (PTSD) can develop after exposure to severe traumatic event. PTSD is associated with changes in behavior and reduced neurogenesis. Available data suggests that antipsychotics or enriched environment may positively affect behavioral outcomes and increase neurogenesis in PTSD patients. Our aim was to determine whether aripiprazole, enriched environment or their combination in the PTSD animal model will positively affect behavioral outcomes and hippocampal neurogenesis. We used the single prolonged stress paradigm to induce PTSD related symptoms in animals. Animals
ePoster · Neuroscience