ePoster · Neuroscience
Cognitive profiles and brain alterations in prodromal and Parkinson's disease individuals
Edith Gaspar, Sarael Alcauter · FENS Forum 2024
We aimed to characterize cognitive profiles and brain morphology correlates of Prodromal and Parkinson's disease (PD) patients from the Parkinson's Progression Markers Initiative program, given the value of detecting Mild Cognitive Impairment (MCI) as a risk factor for dementia in the Prodromal stage. K-means clustering analysis was performed to identify distinct cognitive profiles based on the cognitive domain scores of the Montreal Cognitive Assessment, while volumetric quantification of brain regions was conducted using the AssemblyNet pipeline on T13D MRI brain images. Distinct cognitive p