Topic: astrocyte calcium activity

Recent studies have revealed an essential contribution of cortical astrocyte calcium activity in regulation of sleep depth and state transitions (Bojarskaite et al., 2020, Nat Comms; Vaidyanathan et al., 2021, Nat Comms). However, astrocytic activity is highly heterogeneous across brain regions, and it is unclear if astrocytes mediate sleep transitions in a brain region specific manner. A region of utmost interest to investigate astrocytic activity during sleep is the hippocampus, which not only display high astrocytic heterogeneity (Viana et al., 2023, Glia), but also shows sleep-specific pat