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Topic: astrocytic backbone

ePoster
1 ePoster

In Neuroscience

Assessing histological processing of mouse brain tissue for the reconstruction of tridimensional astrocyte structure

Sara Barsanti, João Luís Machado, João Filipe Viana, Alexandra Veiga, Daniela Sofia Abreu, Duarte Dias, Susana Monteiro, Nuno A. Silva, João Filipe Oliveira · FENS Forum 2024

Astrocytes display complex morphology ranging from multiple main processes stemming from the soma to endfeet and a myriad of leaflets that are in close contact with synapses and other cellular structures. This extended feature, which is heterogeneous across brain regions and physiological states, is pivotal to understanding their dynamic interactions with neighboring neurons and glia. Therefore, assessing astrocytic structures is crucial to understanding their roles in brain networks. Immunostaining for Glial Fibrillary Acidic Protein (GFAP), an astrocyte-specific cytoskeletal protein, is comm

ePoster · Neuroscience