Topic: astrocytic translatome

Astrocytes, the most abundant glial cell population in the central nervous system, play a crucialrole in regulating neuronal networks in response to sensory input changes. Despite their pivotalrole, the molecular basis underlying astrocytic involvement remains largely unexplored. Ourstudy aims to develop a conceptual framework of astrocytic translatome, elucidating theircontribution following sensory deprivation. To achieve this, we employed Aldh1l1-cre/ERT2 xRPL22tm1.1Psam (Ribotag) mice and induced astrocytic-specific ribosome labelling throughtamoxifen administration. Sensory deprivation wa