Mitochondrial origins of sleep pressure control
Raffaele Sarnataro, Cecilia D. Velasco, Nicholas Monaco, Anissa Kempf, Gero Miesenböck · FENS Forum 2024
The neural control of sleep requires that sleep need is sensed during waking and discharged during sleep. While sleep loss has widespread consequences in the whole body and brain, perhaps the only realistic opportunity for separating causation from correlation exists in specialist neurons with active roles in sleep. To obtain an unbiased view of molecular changes in the brain underlying these processes, we characterized the transcriptomes of single sleep-control cells isolated from rested and sleep-deprived flies. Transcripts upregulated after sleep deprivation, in sleep-control neurons projec
ePoster · Neuroscience