GABA transporter 3 (GAT3) is mainly located in the astrocytes in the brain, and it’s responsible for regulating brain inhibitory neurotransmission through the reuptake of GABA molecules from the synapse. Alterations in GAT3 levels are related to multiple neurodegenerative and neurological diseases making it a promising therapeutic target. My research aims to analyze wild-type and C-terminal truncated GAT3 using computational and molecular biology tools to understand the effect of the C-terminal region on the protein’s dynamic, localization, and trafficking. Due to the GAT3 structure being unkn
ePoster · Neuroscience