Postmortem cerebellar volume is not reduced in essential tremor: A comparison with multiple system atrophy and controls
Nathaniel Dunckley, Cecilia Tremblay, Geidy Serrano, Nan Zhang, Kimberly Fiock, Charles Adler, Erika Driver-Dunckley, Shyamal Mehta, Holly Shill, Thomas Beach · FENS Forum 2024
Essential tremor (ET) is a common movement disorder in which cerebellar microscopic and volume alterations have been repeatedly reported although with disagreement between studies. However, pronounced heterogeneity was found with regard to cerebellar volume alterations. This study aimed to assess postmortem cerebellar volume in subjects with or without ET, as compared with subjects with multiple system atrophy (MSA), a well-established cerebellar neurodegeneration. Cases with ET (n = 29), MSA (n = 7), and non-demented control cases without any movement disorder (n = 22) were selected from the
ePoster · Neuroscience