The order and timing of II/III layer activation determine the magnitude and direction of the plastic changes in layer V of the primary motor cortex
Pablo Azón, Samuel Alberquilla, Sara Expósito, Alejandro Hernández Seco, Lucía García Carracedo, Eduardo D. Martín · FENS Forum 2024
The primary motor cortex (MO-p) is a region with a very complex and varied circuitry. It receives inputs from thalamus and other cortical regions, and its outputs goes to cortex, subcortical regions, and medulla, controlling numerous aspects of the motor behavior, as the coordination or the motor learning. The disruption of this system can lead to develop some motor diseases. It is known that glutamatergic neurons of layer II/III project to pyramidal neurons of layer V, putting the inputs and the outputs which goes to medulla and lower brainstem together. However, the plasticity of these conne
ePoster · Neuroscience