Topic: Basal radial glia

Basal radial glia (bRG, also known as oRG) are the main neural progenitor cell subtype implicated in brain evolution. Previous studies showed that the number of bRG morphotypes is higher in species (e.g. primates) with the larger neocortex, an evolutionary newer region of the cerebral cortex, than in species with smaller neocortex (e.g. mice). Therefore, it can be hypothesized that morphotype diversification of bRG is a feature gained in species with expanded neocortex during evolution. To examine this hypothesis, the present study analyzed the morphotypes of bRG in the evolutionary older regi