Pharmacological treatment targeting angiotensin receptor type 2 after severe spinal cord injury improves axonal and myelin regeneration
Veronika Liptakova, Jana Snopková, Erika Hvozdíková, Jaroslav Pavel · FENS Forum 2024
Spinal cord injury represents a complex and serious medical condition characterized by damage to the spinal cord, causing profound functional impairment. The consequences of such an injury may include paralysis, loss of sensation, and disruptions in vital bodily functions, such as bladder and bowel control. The renin-angiotensin system, predominantly acting through the AT1 receptor, regulates blood pressure and hydro-electrolytic balance. However, the AT2 receptor (AT2R) also plays a crucial role, especially in processes related to neuroregeneration. In the present study, the AT2R was stimulat
ePoster · Neuroscience