Therapeutic potential of neurosteroids DHEA and DHEAS in mouse models of Alzheimer’s disease
Barbara Vuić, Tina Miloš, Vladimir Farkaš, Marcela Konjevod, Lucija Tudor, Matea Nikolac Perković, Gordana Nedić Erjavec, Ana Knezović, Jelena Osmanović Barilar, Szidónia Farkas, Adrienn Szabó, Dóra Zelena, Dubravka Švob Štrac · FENS Forum 2024
Dementia is a syndrome characterized by the progressive loss of cognitive functions, predominantly affecting older individuals. It is often accompanied by behavioral and psychological symptoms, significantly impacting dementia prognosis and treatment. Alzheimer's disease (AD) is the most common form of dementia, primarily affecting neurons in the cortex and hippocampus. The main pathological features of AD include extracellular accumulations of amyloid beta peptides in amyloid plaques and intracellular accumulations of hyperphosphorylated tau protein in neurofibrillary tangles. Since there is
ePoster · Neuroscience