Effects of ketogenic diet and BDNF deficiency in mouse chronic restraint stress model
Ilya Smolensky, Kilian Zajac-Bakri, Raphael Guzman, Dragos Inta · FENS Forum 2024
Major depressive disorder (MDD) is a great challenge for psychiatry with up to 40% of treatment-resistant patients. Therefore, non-pharmacological interventions such as different diets seem a promising tool. Ketogenic diet (KD) is a powerful tool for epilepsy and metabolic diseases while new clinical and animal studies show also its potential against mental disorders such as MDD, bipolar disorders and schizophrenia. Several neurobiological pathways have been suggested to mediate effect of KD for the brain and mental health with neurotrophic and neuroplasticity factor BDNF among them. Therefore
ePoster · Neuroscience