Sex-specific network topology of the nociceptive circuit shapes dimorphic behavior in C. elegans
Gal Goldman,Vladyslava Pechuk,Meital Oren-Suissa,Elad Schneidman · COSYNE 2022
The effect of the detailed synaptic connectivity among neurons in a neural circuit on its function and the behavior of the organism, is a key question in many neural systems. C. elegans presents us with a particularly accessible system to explore these relations, thanks to its relative simplicity, the reconstruction of its connectome, and the range of molecular, imaging, and behavioral tools for studying it. We studied here the important circuit for nociception that is composed of the same set of neurons in the two sexes of C. elegans, which are connected in a sexually-dimorphic topology. As t
Thu, Mar 17, 2022