Optimizing electrical stimulation parameters for human-derived neuronal networks: An investigation into the reliability of evoked responses
Giorgia Zanini, Giulia Parodi, Linda Collo, Michela Chiappalone, Sergio Martinoia · FENS Forum 2024
In vitro models of neuronal networks have proven to be a valuable tool for gaining deeper insights into the intricate mechanisms governing the human brain. Notably, the integration of human induced pluripotent stem cells (hiPSCs) with micro-electrode arrays (MEAs) provides a controlled in vitro environment to replicate and analyse both the structural and functional elements of the human brain. As neuronal communication relies on the emission of electrical (and chemical) stimuli, the employment of electrical stimulation becomes crucial for a comprehensive exploration of neuronal assemblies, to
ePoster · Neuroscience