Cilia-mediated cerebrospinal fluid flow modulates neuronal and astroglial activity in the zebrafish larval brain
Percival Paul D'Gama, Inyoung Jeong, Andreas Moe Nygård, Ahmed Jamali, Emre Yaksi, Nathalie Jurisch-Yaksi · FENS Forum 2024
Cerebrospinal fluid (CSF) is a clear, colorless fluid that bathes the central nervous system and is essential for brain homeostasis. CSF flows through interconnected ventricles which are lined by ependymal cells that generate a directional flow upon beating of their motile cilia. Defects in motile cilia can lead to a variety of neurological conditions like hydrocephalus, which is characterized by an accumulation of CSF in the brain. Nevertheless, the function of motile cilia-mediated fluid flow and its impact on brain development and physiology is still poorly understood. To address these ques
ePoster · Neuroscience