Topic: brain-like tissue

Neural stem cell and tissue transplantation offers a promising strategy for central nervous system regeneration. Previous studies have yet to evaluate how the host brain environment in the context of aging effects the ability of the graft to survive and integrate following implantation. The aim of this study was to determine the impact of recipient age on the integration of rat embryonic neural progenitor cells implanted near the subventricular zone (SVZ)-CSF interface. Specifically, embryonic rat neural progenitor cells were implanted near the SVZ of 3-week, 4-month, and 12-month-old rats. Th