Topic: brain-wide functional imaging

The ability to maintain a stable state in the presence of perturbations, known as robustness, is a defining feature of living systems. Most animals demonstrate adaptability by adjusting their position when confronted with external stimuli, a crucial skill for survival. How the brain dynamically regulates behavior in response to a changing environment remains a fundamental question in neuroscience. We investigated it using Danionella cerebrum, the smallest known vertebrate amenable to brain-wide functional imaging at cellular resolution across all developmental stages. We developed a 2D virtual