Strong sexual dimorphism in the evolution of fear memory revealed by brain-wide activation analysis
Alessandra Franceschini, Giacomo Mazzamuto, Curzio Checcucci, Lorenzo Chicchi, Duccio Fanelli, Irene Costantini, Maria Beatrice Passani, Bianca Ambrogina Silva, Francesco Saverio Pavone, Ludovico Silvestri · FENS Forum 2024
Fear responses are functionally adaptive behaviors that are strengthened as memories. Indeed, detailed knowledge of the neural circuitry modulating fear memory could be the turning point for the comprehension of this emotion and its pathological states. A comprehensive understanding of the circuits mediating memory encoding, consolidation, and retrieval presents the fundamental technological challenge of analyzing activity in the entire brain with single-neuron resolution. In this context, we develop the brain-wide neuron quantification toolkit (BRANT) for mapping whole-brain neuronal activati
ePoster · Neuroscience