Alzheimer's disease (AD) is a tauopathy characterized by memory loss and cognitive decline. Tau protein plays a crucial role in the assembly and stabilization of microtubules. In disease conditions, aggregates of misfolded and hyperphosphorylated tau protein leads to neurofibrillary tangles. AD associated neurodegenerative changes in the brain are accompanied by structural of the retina, such as, optic nerve degeneration and reduced thickness of retinal layers. Numerous studies have shown the presence of tau aggregates in both AD mouse models and postmortem samples of AD patients’ retina. The
ePoster · Neuroscience