Topic: burst profile algorithms

The advent of large-scale and high-density ex-vivo experiments enables the unveiling of neural network dynamics at unprecedented resolution. It is now routinely possible to grow neural network cultures from individual human subjects, allowing us to compare the dynamics of subtly different genetic backgrounds. As the analysis of network dynamics becomes more fine-grained, we observed unexplained variability of our results during the development stages of the cultures, beyond the boundaries of genotypic differences. Our work leveraged breakthroughs in culturing cortical neurons from human induce