Topic: C57B6 mice

Hypoxia-ischemia (HI) is a significant cause of disability and mortality in neonates. HI is characterized by acute energetic failure and secondary inflammatory response. The primary therapeutic intervention is hypothermia, which presents limited neuroprotective effects. Environmental approaches, such as skin-to-skin contact, have been highlighted for their benefits in brain development. Oxytocin (OT) is a neuropeptide with roles in parturition and social behavior, but it also modulates the microglial inflammatory responses. Therefore, the study of OT signaling can be helpful to bridge the gap