Topic: CA1 excitatory population activity

Animals and humans acquire knowledge through experience allowing them to flexibly generalize to novel situations. Several findings suggest that the Hippocampus (HC) is involved in the development of this conceptual learning not only for navigational but for other non-spatial variables if relevant to a task. However, how concepts arise with learning and how the hippocampus is involved in building these from the statistical structure of episodic memories still remains unknown. To study this, we trained mice on a binary categorization task consisting of a category split between low and high tone