Topic: CA1 subregion

Neuropeptide Y (NPY) is the most abundant neuropeptide in the brain, co-expressed with other neurotransmitters. It is expressed mainly by interneurons in different regions, including the hippocampus (HP). NPY binds to five G-protein-coupled receptors (R), from which Y1 and Y2 R are the most numerous in the rodent brain. NPY is implicated in the regulation of stress and can exert anxiolytic or anxiogenic effects, depending on the specific brain region and receptor subtype being activated. HP and specifically its ventral portion, contributes to this processing with an important role in emotional