Topic: CA3-CA1

Early experiments studying the effects of lesions of the Hippocampus have reported that recent memories are often unavailable to be retrieved, while old memories are successfully reminded. These observations have led to state the theory of Systems Consolidation. This is the process by which the fast-learning Hippocampus replays the encoded memory during sleep and thus consolidates the corresponding memory in the Neocortex [1]. Formation of memory would take longer in the Neocortex because of its much larger spatial scale compared to the Hippocampus, and thus requires axonal growth and synaptog