Orexin as a neuropsychological basis for temptation-resistant voluntary exercise
Alexander Tesmer, Xinyang Li, Eva Bracey, Cyra Schmandt, Rafael Polania, Daria Peleg-Raibstein, Denis Burdakov · FENS Forum 2024
There is an overwhelming agreement in scientific literature and global health guidelines that physical exercise is beneficial for health. Despite this, many people under-exercise, and instead choose to consume highly-palatable food (HPF) which is widely available in many societies. What neural mechanisms drive the prioritization of exercise, especially in the presence of HPF, remain unclear. We implement a novel paradigm allowing freely-behaving mice to choose between voluntary wheel-running and several other temptations. Mice displayed a clear preference to spending most of their time wheel-r
ePoster · Neuroscience