Spontaneous mesoscale calcium dynamics reflect the development of the modular functional architecture of the mouse cortex
Davide Warm, Davide Bassetti, Levente Gellèrt, Jenq-Wei Yang, Heiko J. Luhmann, Anne Sinning · FENS Forum 2024
The mammalian cerebral cortex presents a modular organization, enabling the segregation of specialized functions and the generation of complex cognitive states. In the mouse, the anatomical and functional correlates of this network topology arise during the perinatal period. Especially after birth, spontaneous neural activity and sensory inputs trigger complex spatio-temporal firing patterns, which affect the cytoarchitecture and connectivity of cortical regions. Thus, understanding how local activity patterns emerge, interact and impinge on cortex-wide dynamics is essential to elucidate the p
ePoster · Neuroscience