Functional heterogeneity of astrocytes in the somatosensory cortex and its role in the processing of different sensory modalities
Andrea Misol Ortiz, Verónica Barranco Maresca, Marta Zaforas, Elena Alonso-Calviño, Elena Fernández-López, Juan Aguilar, Juliana M Rosa · FENS Forum 2024
A primary goal of cortical physiology is to explain how the cortex transforms incoming information to generate precise output behaviour. A recent work from our group show that cortical astrocytes are crucial to set the threshold detection of neuronal circuities across cortical layers to compute specific sensory modalities. But how can astrocyte help to set the sensibility of neurons in a modality-specific manner? By using in vivo electrophysiology and sensory experiments in fosTRAP2 mice, we show that disruption of cortical astrocyte activity impairs the transfer of information across the feed
ePoster · Neuroscience