Plasticity of inhibitory transmission from L1 interneurons of the mouse visual cortex
Adrianna Nozownik, Andrea Aguirre, Alberto Bacci, Joana Lourenço · FENS Forum 2024
A coherent representation of the external world requires the integration of sensory (bottom-up) input with contextual (top-down) information. Contextual signals reach primary cortical sensory areas through layer 1 (L1), the outermost layer of the neocortex. L1 harbors somas of GABAergic interneurons (INs), positioned among dendritic tufts of pyramidal neurons (PNs) and projections originating from cortical and subcortical areas. Neuron-derived neurotrophic factor (NDNF) is expressed by ~70% of the L1 IN population, which was shown to be activated by incoming top-down information. However, how
ePoster · Neuroscience