Novel nanoscale cellular connections between vascular endothelial cells and perivascular glia and between neurons and glia in the developing brain revealed by 3D-EM
Hitoshi Komuro, Nobuhiko Ohno, Aurélien Debonne, Ludovic Galas, Pasko Rakic · FENS Forum 2024
Chemically-mediated signals and physical contact-mediated signals are utilized in wide varieties of cells of the brain to transfer information to each other. For example, chemically-mediated signals provide pivotal communication between vascular endothelial cells and perivascular cells to control local blood circulation. Also, chemically-mediated signals play essential roles in the learning, memory and cognition via mediating communication between neurons. In contrast, the existence and function of nano-scale cell-cell contacts in the brain is not fully understood. This is because, to identify
ePoster · Neuroscience