Fecal microbiota transfer reduces alcohol preference in stressed rats
Léa Aeschlimann, Kshitij Jadhav, Gilbert Greub, Claire Bertelli, Sedreh Nassirnia, Aurélien Thomas, Federicka Gilardi, Benjamin Boutrel · FENS Forum 2024
Alcohol use represents a significant health concern, accounting for 4.5% of global disease burden. Only a small proportion of individuals develop persistent alcohol used disorder though. With current pharmacotherapies largely unsatisfying, discovering novel alternatives to prevent alcohol use disorder becomes a priority. Hence, identifying biological markers predicting vulnerability to develop excessive alcohol consumption may lead to real improvement of clinical care. Converging evidence suggests that gut microbiota is capable of influencing immunity, brain and behavior. We thus investigated
ePoster · Neuroscience