Topic: cerebellar population activity

The cerebellum is critical for locomotor coordination, but it is still not well understood how locomotor signals are represented within the cerebellum to enable whole-body coordination. In particular, while cerebellar Purkinje cell activity is strongly modulated by the locomotor stride cycle, it is not clear how that activity is constructed from its afferent inputs, nor how it can be used for real-time control. To investigate these questions, we are recording cerebellar population activity with Neuropixels probes during locomotion in head-fixed mice, combined with high-speed 3D tracking of lim