Topic: cerebral hemispheres

This study focused on unilateral spatial neglect (USN), a disorder of attention on the contralateral side caused by damage to the cerebral hemispheres. Existing evidence-based rehabilitation for USN is insufficient, prompting the need for an animal model to develop effective treatments. The study aims to establish an aged mouse model of USN targeting the medial agranular cortex, analogous to the human frontal eye field. Focal infarcts were induced in aged mice using photothrombosis, and USN was assessed in an 8-arm radial maze. Mice were given 11 minutes to freely explore the 8-arm radial maze