Topic: cerebro-cerebellar feedback

Circuits connecting the cerebral cortex and cerebellum are essential for sensorimotor control. How do the primary sensorimotor cortical activity and cerebellar activity affect each other during voluntary movement? Whereas the specific anatomical connections have been elucidated in great detail, the neural dynamics that drive sensorimotor behaviour are still unclear. We recorded from primary sensorimotor cortices and cerebellum during whisking in mice and intermittently optogenetically manipulated their activity. Here we unveil that the direction of signals between the cerebral cortex and the c