Topic: choline-acetyltransferase

The lateral septum (LS) integrates diverse subcortical and cortical inputs to generate appropriate affective behavioral responses related to fear, reward, social behaviors, and memory. Contrary to the medial septum (MS) the LS is considered an entirely GABAergic nucleus where neurons express a plethora of GABAergic markers in a partially overlapping manner. In this work, we describe a neglected and underappreciated neuronal subclass in the lateral septum expressing choline-acetyltransferase (ChAT), therefore named Lateral Septum Cholinergic Neurons (LSCNs). ChAT expressing neurons are immunohi