Choroid plexuses carry nodal-like cilia that undergo axoneme regression from early adult stage
Kim Hoa Ho, Adrien Candat, Valentina Scarpetta, Marion Faucourt, Solene Weill, Chiara Salio, Elisa D’Este, Martin Meschkat, Christian A. Wurm, Matthias Kneussel, Carsten Janke, Maria M. Magiera, Auguste Genovesio, Alice Meunier, Marco Sassoè-Pognetto, Monika S. Brill, Nathalie Spassky, Annarita Patrizi · FENS Forum 2024
Choroid plexus (ChP) is located in cerebral ventricles, where it produces cerebrospinal fluid (CSF), forms the selective blood-CSF barrier and controls the homeostasis of the central nervous system. ChP is primarily composed of a monolayer of specialized epithelial cells producing cerebrospinal fluid. Differentiated ChP epithelial cells harbor multiple cilia on the CSF-facing surface, but their development and function are still controversial. We have delineated the sequential progression of cilia formation in the ChP epithelial cells by exploiting super-resolution microscopy techniques and mo
ePoster · Neuroscience