ClearFinder: A Python GUI for annotating cells in cleared mouse brain
Margarita Tevosian, Stefan Pastore, Philipp Hillenbrand, Nils Molnar, Irina Kovlyagina, Monika Chanu Chongtham, Stanislav Sys, Beat Lutz, Susanne Gerber · FENS Forum 2024
Tissue clearing combined with light-sheet microscopy is gaining popularity among neuroscientists interested in unbiased assessment of their samples in 3D volume, while the analysis of such data remains a challenge. ClearMap and CellFinder are tools for analysing neuronal activity maps in an intact volume of cleared mouse brains. However, these tools lack a user interface, restricting accessibility primarily to scientists proficient in advanced Python programming. The present application aims to bridge this gap and make the data analysis accessible for a wider scientific community. We develop
ePoster · Neuroscience