Topic: Climbing Fiber

Understanding dendritic integration in relation to its excitatory and inhibitory inputs is critical to deciphering neuronal data processing. Upon sensorimotor stimulus, the cerebellar Purkinje neuron (PN) receives excitatory inputs from a single climbing fiber (CF), thousands of parallel fibers (PFs), and feed-forward inhibitory inputs (FFI) from molecular layer interneurons (MLIs). This study aims to understand the dendritic interplay of MLI inhibitory inputs, shaping excitatory inputs upon air puff stimulation in awake mice.We labeled MLI axons with GCaMP6 and PN with the voltage-sensitive d