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Topic: clustered adaptive integrate-and-fire neurons

ePoster
1 ePoster

In Artificial Intelligence and Biology

ePoster · Computational Neuroscience

Deep inverse modeling reveals dynamic-dependent invariances in neural circuits mechanisms

Richard Gao, Michael Deistler, Auguste Schulz, Pedro Gonçalves, Jakob Macke · Bernstein Conference 2024

Neural population dynamics are jointly shaped by numerous factors at the cellular, synaptic, and network levels. Mechanistic models, especially spiking neural networks, are crucial for understanding how these interacting variables influence neural activity. However, the process of adjusting model parameters to match experimental recordings, i.e., inverse modeling, is challenging, and often requires a trade-off between model complexity and tractability. Consequently, models often use fixed or manually tuned parameters, limiting their dynamic range and explanatory power while making cross-study