The subthalamic nucleus hyperdirect pathway neural dynamics during cocaine use and 'natural' reward seeking behavior – a pilot study
Maya Williams, Mohamed Mounir El Mendili, Christelle Baunez, Mickaël Degoulet · FENS Forum 2024
The increasing burden of drug addiction on society and the challenge of treating addicts has been the focus of much research in the past decades. The subthalamic nucleus (STN) has been shown to be a very interesting target since its inactivation by lesion or Deep Brain Stimulation can reduce motivation for cocaine, while increasing motivation for sweet food. Since the STN is a hub of the Basal ganglia and receives direct cortical projections (the hyperdirect pathway) it is important to clarify the role of this pathway in the effects observed after STN manipulations. This study thus seeks to cl
ePoster · Neuroscience