Dendritic low pass filtering shapes midbrain neural responses to behaviorally relevant stimuli
Norma Kühn, Bram Nuttin, Chen Li, Natalia Baimacheva, Katja Reinhard, Vincent Bonin, Karl Farrow · COSYNE 2023
Neurons are equipped with powerful analog processing units – dendrites. However, the role linear and nonlinear dendritic properties play in shaping a neuron’s output to filter behaviorally relevant information and subsequently drive behavior, is poorly understood. Here, we address this question using wide-field neurons of the mouse superior colliculus; a genetically targetable midbrain cell-type that receives direct input from the retina and mediates innate defensive and hunting behaviors. To understand how wide-field neurons combine their inputs, we measured their output: the responses to beh
Sat, Mar 11, 2023