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Topic: CommonMind data set

ePoster
1 ePoster

In Neuroscience

Differential expression and enrichment analysis of brain energy metabolism genes in schizophrenia

Ilona Mäkinen, Marja-Leena Linne, Tuomo Mäki-Marttunen · FENS Forum 2024

AbstractSchizophrenia is mental disorder characterized by a large variety of symptoms such as paranoia, delusions, lack of motivation and problems in attention and memory. In recent years it has been hypothesized that mitochondrial dysfunction and energy metabolism dysregulation may contribute to the pathophysiology of schizophrenia [1]. Therefore, we studied the mRNA expression of the prefrontal cortex (PFC) using the CommonMind data set [2] to find out if there is a significant enrichment of differentially expressed metabolism genes between control group and schizophrenia patients. In additi

ePoster · Neuroscience