Comparative study of lipidomic changes in human brain affected by schizophrenia and major depressive disorder
Dmitry Senko, Olga Efimova, Maria Osetrova, Elena Stekolshchikova, Philipp Khaitovich · FENS Forum 2024
The molecular nature of psychiatric disorders such as schizophrenia and major depression is still unclear. Lipids may play an important role in the understanding of these disorders, as they are the most abundant yet poorly studied components of the human brain. In this work, we present a comparative lipidomic map of the human brain affected by schizophrenia or major depressive disorder. The study involved three groups of donors, 7 donors each, which included schizophrenic and depressive donors as well as healthy controls. The lipid composition of 36 brain regions was evaluated by liquid chroma
ePoster · Neuroscience