Topic: compulsive drug-seeking

Drug addiction is a chronic relapsing disorder characterized by compulsive drug-seeking. There is lot of interest in gaining a better understanding of how acupuncture works in the brain to modulate addictive behaviors. The current study aims to discuss the neurobiological mechanisms underlying acupuncture’s effectiveness in the treatment of drug addiction, on the basis of two different theories (the incentive sensitization theory and the opponent process theory) that have seemingly opposite views on the role of the mesolimbic reward pathways in mediating compulsive drug-seeking behavior. Resul