Astrocytes in globus pallidus externa integrate sensory information through dopamine D2 receptors
Zisis Bimpisidis, Fabrizio Bernardi, Francesca Managò, Daniel Dautan, Maria Antonietta De Luca, Francesco Papaleo · FENS Forum 2024
The globus pallidus externa (GPe) is a basal ganglia structure with a high content of astrocytes compared to neighboring brain regions. Apart from its well-known role in locomotor behavior, recent studies showed that the GPe is also involved in cognitive functions, motivated behavior and sensory integration. The vast majority of studies has focused on neuronal subpopulations in GPe, while the function of the numerically superior astrocytes remain elusive. Recently, we showed that astrocytes in GPe express dopamine D2 receptors (D2Rs), and their selective manipulation can have profound effects
ePoster · Neuroscience